What is the main function of T helper cells in the immune response?

The main function of T helper cells in the immune response is to assist B cells in producing antibodies. T helper cells, specifically the CD4+ subset, play a crucial role in the adaptive immune system. They enhance the activation and proliferation of B cells, which are responsible for the production of antibodies. When B cells encounter an antigen, T helper cells recognize this antigen presented on Major Histocompatibility Complex (MHC) class II molecules. Through various signaling mechanisms and the release of cytokines, T helper cells promote B cell activation, differentiation, and ultimately, the generation of high-affinity antibodies that are specific to the antigen.

Although T helper cells are involved in various immune functions, including the secretion of lymphokines, their primary role in the context of antibody production is what makes the option about assisting B cells particularly relevant. This interaction is a pivotal part of the humoral immune response, which is essential for effectively targeting extracellular pathogens. Other options may describe functions of different immune cells but do not capture the essence of T helper cell activity in relation to B cells and antibody formation.