What condition is characterized by immune deficiency and is associated with thrombocytopenia present at birth?

Wiskott-Aldrich syndrome is indeed characterized by immune deficiency and is notable for its association with thrombocytopenia from birth. This condition is an X-linked recessive immunodeficiency disorder that affects mostly males. In Wiskott-Aldrich syndrome, individuals present with a classic triad of symptoms: eczema, recurrent infections due to immune deficiency, and low platelet counts (thrombocytopenia). This triad is crucial for the diagnosis and differentiates it from other immunodeficiencies.

The association with thrombocytopenia is particularly significant because it's a key feature of the disorder, occurring early in life. The immunodeficiency in Wiskott-Aldrich syndrome results primarily in a defect in both humoral and cell-mediated immunity, which leads to a higher susceptibility to infections.

Other conditions listed might exhibit problems with the immune system, but they do not have the classic combination of symptoms including congenital thrombocytopenia. DiGeorge syndrome, for instance, is primarily a result of a chromosomal deletion and presents with a range of symptoms including cardiac defects and hypoparathyroidism, but it does not typically feature thrombocytopenia. HIV/AIDS involves immune deficiency but develops later in life and is not linked with thromb