Most antibodies migrate in which region during serum protein electrophoresis?

During serum protein electrophoresis, antibodies primarily migrate within the gamma region of the gel. This region is designated for immunoglobulins, which are the proteins responsible for immune responses in the body.

The gamma globulins include various types of antibodies, such as IgG, IgA, IgM, IgD, and IgE. These immunoglobulins are crucial for their roles in recognizing and neutralizing pathogens, and they typically exhibit a higher negative charge at physiological pH, allowing them to migrate further during electrophoresis.

The alpha and beta regions mainly contain other proteins, such as albumin and various enzymes, while the delta region is relatively less defined and does not specifically correspond to immunoglobulins. Thus, the correct identification of the gamma region as the primary area for antibody migration highlights the important roles that immunoglobulins play in the immune function of serum proteins.